snippet How Astrocytic TDP-43 protein accumulation and dysregulation accelerate neurodegeneration When most people think of neurodegenerative disease, they probably think of the loss of neurons and corresponding loss of memories or cognitive function. This expected relationship between neurons and neurodegenerative disease makes sense. After all, neurons are the cells that send information throughout the
snippet Towards the Effective and Safe Treatment of Psychosis and Alzheimer’s Disease In the U.S. alone, there are 6.2 million people living with Alzheimer’s Disease (AD), the most common form of dementia [1]. While this unfortunate reality is generally recognized by the public, a lesser-known fact is that approximately 50% of those suffering
Issue 28 The Hunt for a Cure: Promising New Developments in Huntington’s Disease Research When discussing her grandmother’s and father’s diagnoses with Huntington’s Disease (HD), Kimberly Pryce described the testing process as “a flip of a coin. Heads, you’re facing
Issue 27 Spice Spice Baby: How Eating Spices Benefits the Brain Imagine you’re out at dinner with a friend, excitedly awaiting your dish. Your food comes, and you take a big bite.
Issue 26 Gene Therapy: Treating the Untreatable If you asked researchers for a list of the last decade’s most important discoveries, most would include CRISPR-Cas9, a system that has the ability to find a sequence within a strand of DNA, cut it out, and replace it with a new sequence.
Issue 15 FOXO Transcription Factors and Neurodegenerative Diseases Neurodegenerative diseases such as Alzheimer’s and Parkinson’s are tragic conditions that cause the loss of memory and motor control. As these diseases progress, patients eventually forget everything, including
Issue 14 The Blood Brain Barrier Baffles Big Pharma Despite there being a large unmet need for treatments in neurological disorders, big pharma is beginning to withdraw from drug development due to the challenge of crossing the blood-brain barrier,
Issue 14 A New Approach to Huntington’s Among inherited neurodegenerative disorders, Huntington’s Disease (HD) is the most common. [1] HD is a grim diagnosis, for the disease not only takes lives but also leaves the descendants
Issue 11 Motor Neuron Disease Our nervous system, generally speaking, is composed of three types of neurons: sensory, motor, and interneurons. Together, these neurons create pathways that transmit signals from all across our bodies via
Issue 4 The Cellular Basis of Neurodegenerative Disease Neurodegenerative disease is on the mind of the American public. More than five million Americans are living with Alzheimer’s disease, and this number is expected to increase in coming
